Cardiac Vascular Nursing Certification Practice Exam

The primary function of angiotensin-converting enzyme (ACE) is to convert angiotensin I to angiotensin II. This process is a critical step in the renin-angiotensin-aldosterone system (RAAS), which plays a significant role in regulating blood pressure and fluid balance in the body.

Angiotensin I is an inactive precursor that is formed from angiotensinogen, which is produced by the liver. When angiotensin I is released into the bloodstream, ACE, which is mainly found in the lungs, converts it into the active hormone angiotensin II. Angiotensin II has several important functions, including promoting vasoconstriction, stimulating the release of aldosterone from the adrenal glands, and increasing the reabsorption of sodium and water in the kidneys, all of which contribute to an increase in blood pressure.

Understanding the role of ACE is vital for recognizing how various cardiovascular and renal conditions are treated, particularly with the use of ACE inhibitors, which are commonly prescribed to lower blood pressure and protect kidney function by preventing the conversion of angiotensin I to angiotensin II.